Abstract Objective JARID2 is a member of chromatin-modifying Polycomb Repressive Complex-2 or PRC2.It Blankets plays a role in recruiting PRC2 to developmental genes and regulating its activity.JARID2 along with PRC2 is indispensable for normal development.However, it remains unclear how JARID2 expression itself is regulated.Recently a number of no
Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment
Abstract Background Previous studies on the role of TP53 mutation in breast cancer treatment response and survival are contradictory and inconclusive, limited by the use of different endpoints to determine clinical significance and by small sample sizes that prohibit stratification by treatment.Methods We Blankets utilized large datasets to examine
Visual feedback of hand and target location does not explain the tendency for straight adapted reaches.
Subjects in laboratory settings exhibit straight hand paths-typified by the minimum jerk path-even in the presence of a learned but disturbing force field.At the same time it is known that in this setting, visual feedback strongly influences reaches, biasing them to be straight.Here we examine whether or not this bias can account for the straightne
Sclerouveitis with exudative retinal detachment associated with chronic myelomonocytic leukemia
Purpose: To describe a case of sclerouveitis with exudative retinal detachment in a patient with chronic myelomonocytic leukemia.Observations: An 82-year-old woman with chronic myelomonocytic leukemia (CMML) presented with acute painful right eye redness and decreased visual acuity.Examination revealed right eye anterior and posterior scleritis wit
Surveillance, contact tracing and characteristics of SARS-CoV-2 transmission in educational settings in Northern Italy, September 2020 to April 2021.
BackgroundThe role of school contacts in the spread of the virus and the effectiveness of school closures in controlling the epidemic is still debated.We aimed to quantify COLLAGEN ORANGE the risk of transmission of SARS-CoV-2 in the school setting by type of school, characteristics of the index case and calendar period in the Province of Reggio Em